Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia.

@article{Gulley2010GeneticTT,
  title={Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia.},
  author={Margaret L Gulley and Thomas Charles Shea and Yuri Fedoriw},
  journal={The Journal of molecular diagnostics : JMD},
  year={2010},
  volume={12 1},
  pages={
          3-16
        }
}
Management of patients with acute myeloid leukemia relies on genetic tests that inform diagnosis and prognosis, predict response to therapy, and measure minimal residual disease. The value of genetics is reinforced in the revised 2008 World Health Organization acute myeloid leukemia classification scheme. The various analytic procedures-karyotype, fluorescence in situ hybridization, reverse transcription polymerase chain reaction, DNA sequencing, and microarray technology-each have advantages… CONTINUE READING
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