Genetic testing in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease.

@article{Wu2004GeneticTI,
  title={Genetic testing in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease.},
  author={Y R Wu and Hai Lin and Chiung Mei Chen and Katrina Gwinn-Hardy and Long Sun Ro and Ying-Chieh Wang and Sophia Hsin-Jung Li and John C. Hwang and K Fang and Hsiu Mei Hsieh-Li and Mischa Li and Lai Tung and Ming-Yen Thomas Su and Kristina T. Lu and Guey-Jen Lee-Chen},
  journal={Clinical genetics},
  year={2004},
  volume={65 3},
  pages={209-14}
}
DNA tests in normal subjects and patients with ataxia and Parkinson's disease (PD) were carried out to assess the frequency of spinocerebellar ataxia (SCA) and to document the distribution of SCA mutations underlying ethnic Chinese in Taiwan. MJD/SCA3 (46%) was the most common autosomal dominant SCA in the Taiwanese cohort, followed by SCA6 (18%) and SCA1… CONTINUE READING