Genetic testing in nephrotic syndrome—challenges and opportunities

  title={Genetic testing in nephrotic syndrome—challenges and opportunities},
  author={Rasheed A. Gbadegesin and Michelle P. Winn and William E. Smoyer},
  journal={Nature Reviews Nephrology},
Monogenic nephrotic syndrome (nephrotic syndrome caused by a single gene defect) is responsible for only a small percentage of cases of nephrotic syndrome, but information from studies of the unique cohort of patients with this form of the disease has dramatically improved our understanding of the disease pathogenesis. The use of genetic testing in the management of children and adults with nephrotic syndrome poses unique challenges for clinicians in terms of who to test and how to use the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 9 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 21 extracted citations


Publications referenced by this paper.
Showing 1-10 of 50 references

Clinical utility of genetic testing in children and adults with steroidresistant nephrotic syndrome

  • S Santín
  • Clin. J. Am. Soc. Nephrol
  • 2011

Effect of cyclosporin A on proteinuria in the course of glomerulopathy associated with WT1 mutations

  • Wasilewska, M A.
  • Eur. J. Pediatr. 170,
  • 2011

Similar Papers

Loading similar papers…