Genetic testing for von Willebrand disease: the Canadian experience.

@article{James2006GeneticTF,
  title={Genetic testing for von Willebrand disease: the Canadian experience.},
  author={Paula D James and David P. Lillicrap},
  journal={Seminars in thrombosis and hemostasis},
  year={2006},
  volume={32 5},
  pages={546-52}
}
Von Willebrand disease (vWD) is the most common inherited bleeding disorder in humans, but its diagnosis, using clinical criteria and phenotypic hemostasis test results, can be problematic. Since the cloning of the von Willebrand factor ( VWF) gene in the mid-1980s, a significant amount of information has been gathered with respect to the molecular pathology responsible for this trait. The extent of this information, along with major advances in genetic technology, has now made the integration… CONTINUE READING

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