Genetic systems for functional cell ablation in Drosophila.

  title={Genetic systems for functional cell ablation in Drosophila.},
  author={Sean T Sweeney and Alicia Hidalgo and J. Steven de Belle and Haig Keshishian},
  journal={Cold Spring Harbor protocols},
  volume={2012 9},
The selective removal of cells by ablation is a powerful tool in the study of eukaryotic developmental biology, providing much information about the origin, fate, or function of these cells in the developing organism. In Drosophila, three main methods have been used to ablate cells: chemical, genetic, and laser ablation. Each method has its own applicability with regard to developmental stage and the cells to be ablated, and its own limitations. This article describes genetic systems for… CONTINUE READING