Genetic susceptibility to pancreatic cancer.

  title={Genetic susceptibility to pancreatic cancer.},
  author={Alison P Klein},
  journal={Molecular carcinogenesis},
  volume={51 1},
Pancreatic cancer is the fourth leading cause of cancer death in both men and women in the United States. However, it has the poorest prognosis of any major tumor type, with a 5-yr survival rate of approximately 5%. Cigarette smoking, increased body mass index, heavy alcohol consumption, and a diagnosis of diabetes mellitus have all been demonstrated to increase risk of pancreatic cancer. A family history of pancreatic cancer has also been associated with increased risk suggesting inherited… CONTINUE READING


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