Genetic susceptibility to male infertility: news from genome‐wide association studies

@article{Aston2014GeneticST,
  title={Genetic susceptibility to male infertility: news from genome‐wide association studies},
  author={K. I. Aston},
  journal={Andrology},
  year={2014},
  volume={2}
}
  • K. I. Aston
  • Published 2014
  • Biology, Medicine
  • Andrology
    • A thorough understanding of the genetic basis of male infertility has eluded researchers in spite of significant efforts to identify novel genetic causes of the disease, particularly over the past decade. Approximately half of male factor infertility cases have no known cause; however, it is likely that the majority of idiopathic male factor infertility cases have some unidentified genetic basis. Well‐established genetic causes of male infertility are limited to Y chromosome microdeletions and… CONTINUE READING
    View on Wiley
    onlinelibrary.wiley.com
    Top 3 of 30 Citations
    Recent advances in the genetics of testicular failure
    Seung-Hun Song, K. Chiba, … D. LambAsian journal of andrology2016
    36
    GENETIC CAUSES OF TESTICULAR FAILURE Human spermatogenesis, which takes about 3 months, depends on the co-ordinated action of thousands of testis-specific genes for satisfactory completion of meiosis. It is a complex series of very delicate events
    Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.
    N. Skakkebaek, E. Rajpert-De Meyts, … A. JuulPhysiological reviews2016
    323
    30 Citations
    Citation Type

    Citation Type

    Recent advances in the genetics of testicular failure
    • 36
    GENETIC CAUSES OF TESTICULAR FAILURE Human spermatogenesis, which takes about 3 months, depends on the co-ordinated action of thousands of testis-specific genes for satisfactory completion of meiosis. It is a complex series of very delicate events
      Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.
      • 323
      • PDF
      Genetic intersection of male infertility and cancer.
      • 14
      Single gene defects leading to sperm quantitative anomalies
      • 26
      • PDF
      Genetics of Male Infertility
      • 22
      The evolving role of genetic tests in reproductive medicine
      • 8
      Some of the Factors Involved in Male Infertility: A Prospective Review
      • 3
      • PDF
      Male Infertility as a Marker of Future Health
      Harnessing the full potential of reproductive genetics and epigenetics for male infertility in the era of "big data".
      • 1

      References

      Publications referenced by this paper.
      SHOWING 1-10 OF 29 REFERENCES
      Genetics of human male infertility.
      • 275
      • PDF
      The search for SNPs, CNVs, and epigenetic variants associated with the complex disease of male infertility
      • 38
      Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.
      • 120
      A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation
      • 86
      • Highly Influential
      • PDF
      Genome-wide association study identifies candidate genes for male fertility traits in humans.
      • 102
      High Resolution X Chromosome-Specific Array-CGH Detects New CNVs in Infertile Males
      • 66
      Genome-wide screening of severe male factor infertile patients using BAC-array comparative genomic hybridization (CGH).
      • 12
      Array comparative genomic hybridization in male infertility.
      • 39
      • PDF
      Human Spermatogenic Failure Purges Deleterious Mutation Load from the Autosomes and Both Sex Chromosomes, including the Gene DMRT1
      • 98
      • PDF
      Population stratification and spurious allelic association
      • 1,150
      • PDF