Genetic susceptibility to family environment: BDNF Val66met and 5-HTTLPR influence depressive symptoms.

@article{Dalton2014GeneticST,
  title={Genetic susceptibility to family environment: BDNF Val66met and 5-HTTLPR influence depressive symptoms.},
  author={Elizabeth D Dalton and Constance L. Hammen and Jake M Najman and Patricia A. Brennan},
  journal={Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association},
  year={2014},
  volume={28 6},
  pages={947-56}
}
Functional genetic polymorphisms associated with Brain-Derived Neurotrophic Factor (BDNF) and serotonin (5-HTTLPR) have demonstrated associations with depression in interaction with environmental stressors. In light of evidence for biological connections between BDNF and serotonin, it is prudent to consider genetic epistasis between variants in these genes… CONTINUE READING