Genetic susceptibility to atherosclerosis.

  title={Genetic susceptibility to atherosclerosis.},
  author={J C Chamberlain and D. J. Galton},
  journal={British medical bulletin},
  volume={46 4},
Genetic factors are implicated in atherogenesis by family and twin studies of coronary artery disease, interacting with the environment to produce the phenotypic disease. Restriction fragment length polymorphisms provide useful linkage markers with which to study the genetics of this disease, the effectiveness of marker loci being characterized in terms of their polymorphism information content. Other forms of nucleotide variation, including variable number of tandem repeats can also provide… CONTINUE READING