Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men

@article{Safarinejad2011GeneticSO,
  title={Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men},
  author={Mohammad Reza Safarinejad and Nayyer Shafiei and Shiva Safarinejad},
  journal={Medical Oncology},
  year={2011},
  volume={28},
  pages={398-412}
}
We performed a case–control study of 158 bladder transitional cell carcinoma (TCC) cases and 316 controls to investigate the association between methylenetetrahydrofolate reductase (MTHFR) C677T, A1298G, and G1793A polymorphisms and bladder cancer susceptibility by polymerase chain reaction restriction fragment length polymorphism (PCR-RLFP) technique. The controls were frequency-matched to the cases by age (±5 years), ethnicity, and smoking status. We also measured serum levels of total… CONTINUE READING

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