Genetic subdivision and candidate genes under selection in North American grey wolves

@article{Schweizer2016GeneticSA,
  title={Genetic subdivision and candidate genes under selection in North American grey wolves},
  author={Rena M. Schweizer and Bridgett M. vonHoldt and Ryan J. Harrigan and James C. Knowles and Marco Musiani and David W. Coltman and John Novembre and Robert K. Wayne},
  journal={Molecular Ecology},
  year={2016},
  volume={25}
}
Previous genetic studies of the highly mobile grey wolf (Canis lupus) found population structure that coincides with habitat and phenotype differences. We hypothesized that these ecologically distinct populations (ecotypes) should exhibit signatures of selection in genes related to morphology, coat colour and metabolism. To test these predictions, we quantified population structure related to habitat using a genotyping array to assess variation in 42 036 single‐nucleotide polymorphisms (SNPs… 
Genomics, environment and balancing selection in behaviourally bimodal populations: The caribou case
TLDR
It is suggested that the underlining balancing force, NFDS, plays a strong role within populations harbouring multiple haplotypes and phenotypes, as it is the norm in animals, plants and humans too.
Targeted capture and resequencing of 1040 genes reveal environmentally driven functional variation in grey wolves
TLDR
This study demonstrates that combining genomewide genotyping arrays with large‐scale resequencing and environmental data provides a powerful approach to discern candidate functional variants in natural populations.
Natural Selection and Origin of a Melanistic Allele in North American Gray Wolves
TLDR
Using population genetic simulations, it is shown that the K locus is undergoing natural selection in four wolf populations, and evidence for balancing selection is found in Yellowstone wolves, which could be a result of selection for enhanced immunity in response to distemper.
Individual-based population genomics reveal different drivers of adaptation in sympatric fish
TLDR
This study studied two sympatric fish species in the Western Mediterranean Sea and identified in both species candidate regions for local adaptation by combining outlier analysis with environmental and phenotypic association analyses, suggesting that different drivers may determine genomic diversity and differentiation in each species.
Signatures of adaptive divergence among populations of an avian species of conservation concern
TLDR
The results provide a first look at local adaption for isolated populations of a single species and suggest adaptive divergence in multiple metabolic and biochemical pathways may be occurring.
Genomic footprints of adaptation in a cooperatively breeding tropical bird across a vegetation gradient
TLDR
It is suggested that selective factors acting along a vegetation gradient can promote local adaptation in the presence of gene flow in a vagile, nonmigratory and geographically restricted species.
Admixture mapping identifies introgressed genomic regions in North American canids
TLDR
It is shown that grey wolf and coyote admixture has far‐reaching effects and, in addition to phenotypically transforming admixed populations, allows for the differential movement of alleles from different parental species to be tested in new genomic backgrounds.
Genetic structure of immunologically associated candidate genes suggests arctic rabies variants exert differential selection in arctic fox populations
TLDR
Using a targeted, genotyping-by-sequencing assay, correlations of arctic fox immunogenetic variation with arctic rabies variants are assessed to gain further insight into the epidemiology of this disease and contribute to the understanding of the co-evolutionary relationships between ar Arctic rabies and their primary host.
Strong phenotypic divergence in spite of low genetic structure in the endemic Mangrove Warbler subspecies (Setophaga petechia xanthotera) of Costa Rica
TLDR
An important role for salinity, forest structure, and resource availability in maintaining phenotypic divergence of Mangrove Warblers through natural selection is indicated.
High gene flow in the American badger overrides habitat preferences and limits broadscale genetic structure
TLDR
The data revealed an overall lack of ecologically based population genetic structure, suggesting that high dispersal capabilities were sufficiently realized to overcome most habitat‐based genetic structure.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 120 REFERENCES
Ecological factors drive differentiation in wolves from British Columbia
TLDR
It is proposed that dispersing grey wolves select habitats similar to the one in which they were reared, and that this differentiation is maintained largely through behavioural mechanisms, suggesting that ecological factors are driving wolf differentiation in British Columbia.
Historical and ecological determinants of genetic structure in arctic canids
TLDR
Results presented here suggest that, through its influence on sea ice, vegetation, prey dynamics and distribution, continued arctic climate change may have effects as dramatic as those of the Pleistocene on the genetic structure of arctic canid species.
Genome-wide signatures of population bottlenecks and diversifying selection in European wolves
TLDR
The results suggest a continuous decline in wolf numbers in Europe since the Late Pleistocene, and long-term isolation and bottlenecks in the Italian and Iberian populations following their divergence from the Eastern European population.
Climate and habitat barriers to dispersal in the highly mobile grey wolf
TLDR
It is found that, contrary to a previous report, a pattern of isolation with distance is evident on a continental scale in the North American wolf population and vegetation types appear to play a role in the genetic dissimilarities among populations.
Footprints of selection in wild populations of Bicyclus anynana along a latitudinal cline
TLDR
It is discussed that the observed clinal variation and elevated population divergence in UGP and Treh may reflect adaptation to a geographic thermal gradient.
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
TLDR
It is shown that dog breeds share a higher proportion of multi-locus haplotypes unique to grey wolves from the Middle East, indicating that they are a dominant source of genetic diversity for dogs rather than wolves from east Asia, as suggested by mitochondrial DNA sequence data.
A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids.
TLDR
It is found that these enigmatic canids are highly admixed varieties derived from gray wolves and coyotes, respectively, and divergent genomic history suggests that they do not have a shared recent ancestry as proposed by previous researchers.
Differentiation of tundra/taiga and boreal coniferous forest wolves: genetics, coat colour and association with migratory caribou
TLDR
Findings show that substantial genetic and phenotypic differentiation in highly mobile mammals can be caused by prey–habitat specialization rather than distance or topographic barriers, and highlights the need to preserve migratory populations.
Selection Signatures in Worldwide Sheep Populations
TLDR
The newly identified regions of selection signatures in worldwide sheep populations reveal the extensive genome response to selection on morphology, color and adaptation to new environments.
Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency
TLDR
This work combines population genetics data with ecological information to detect variants that increased in frequency in response to new selective pressures, and finds particularly strong signals associated with polar ecoregions, with foraging, and with a diet rich in roots and tubers.
...
1
2
3
4
5
...