Genetic sub-types of human malignant astrocytoma correlate with survival.

  title={Genetic sub-types of human malignant astrocytoma correlate with survival.},
  author={S. Leenstra and N T Oskam and Engelien H. Bijleveld and D. Andries Bosch and Dirk Troost and T. Hulsebos},
  journal={International journal of cancer},
  volume={79 2},
In human malignant astrocytoma, age of the patient and histological grade of the tumor are important prognostic variables. Several genetic changes have been reported to occur in these tumors, which may be of additional and independent prognostic relevance. To determine their prognostic significance, we analyzed 75 high-grade tumors, 12 anaplastic astrocytomas and 63 glioblastomas multiforme, for the presence of genetic changes that occur frequently in high-grade astrocytoma, i.e., loss of… CONTINUE READING

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