Genetic study of Dravidian castes of Tamil Nadu

  title={Genetic study of Dravidian castes of Tamil Nadu},
  author={S. Kanthimathi and M. Thirumagal Vijaya and Arabandi Ramesh},
  journal={Journal of Genetics},
The origin and settlement of Indian people still intrigues sci-entists studying the impact of past and modern migrationson the genetic diversity and structure of contemporary pop-ulations. About 10,000 years ago, proto-Dravidian Neolithicfarmers from Afghanistan entered the Indian subcontinent,and were later displaced southwards by a large influx ofIndo–European speakers ∼3500 years ago (Majumder 


The Indian sub-continent is one of the important constituent of South Asia with reservoir of enormous socio-cultural, racial and genetic diversities. Central India in particular has been a vibrant

Genomic Diversity and Affinities among Four Dravidian Tribal Populations of South India: A Study on Eighteen Autosomal DNA Markers

DNA samples from 190 unrelated individuals belonging to four Dravidian tribal populations were analysed by nine human specific insertion / deletion polymorphic loci and nine restriction site polymorphIC loci to ascertain their genomic diversity and affinities with other Indian tribal populations.

Alu Insertion/Deletion Polymorphism in Four Tribes of South India

The results reveal that the study populations have received moderate gene flow compared to other populations, and all the studied biallelic loci are highly polymorphic in terms of allele frequencies and average heterozygosity.

Autosomal DNA Polymorphisms of Four South India Tribal Populations

To examine what evolutionary forces have most significantly impacted south Indian tribal genetic variation, and to test whether the phenotypic similarities of some south India tribal groups to Africans represent a signature of close relationship to Africans or are due to convergence.

Unity in diversity: an overview of the genomic anthropology of India

The results show that Indian populations have a higher level of unique genetic diversity which is structured by many social processes and geographical attributes of the country.

Polymorphic Alu Insertion/Deletion in Different Caste and Tribal Populations from South India

This study firmly established the genetic relationship of South Indian castes and tribes and supported the proposed large scale ancestral migrations from Africa, particularly into South India through West Asian corridor.

Genetic admixture studies on four in situ evolved, two migrant and twenty-one ethnic populations of Tamil Nadu, south India

Haplogroup frequencies indicate that various ethnic groups entered Tamil Nadu during different time periods, and genetic affinities and admixture estimates revealed that the ethnic groups possessing advanced knowledge of farming cluster in a branch (C) was introduced to this region at about 5 to 3 thousand years ago.

Association of ACE DD genotype with Hypertension among the tribal populations of South India

This study examined the distribution of ACE I/D polymorphisms in their association with Hypertension among the tribal populations of Southern India and found the DD genotype to be associated with hypertension among the tribes of South India.



A Genetic Structure of the Early Immigrants (Mukkalathor) of Tamil Nadu as Inferred From Autosomal Loci

Genomic affinity based on eight human – specific polymorphic insertion/ deletion loci was studied in an early immigrant population, Thevar group, of Tamil Nadu, South India, and showed high levels of polymorphism, thereby reflecting their common ancestry.

Genetic structure and affinities among tribal populations of southern India: a study of 24 autosomal DNA markers

It is concluded that the phenotypic similarities of some Indian groups to Africans do not reflect a close relationship between these groups, but are better explained by convergence.

Searching for the Origins of Indo-European Languages@@@Archaeology and Language: The Puzzle of Indo-European Origins

New edition of a classic previously published since 1987 by Penguin. Renfrew considers questions of language origins and what they imply about ethnic affiliation. He re-examines the problem of the

Ethnic India: a genomic view, with special reference to peopling and structure.

We report a comprehensive statistical analysis of data on 58 DNA markers (mitochondrial [mt], Y-chromosomal, and autosomal) and sequence data of the mtHVS1 from a large number of ethnically diverse

Human-specific insertion/deletion polymorphisms in Indian populations and their possible evolutionary implications

DNA samples from 396 unrelated individuals belonging to 14 ethnic populations of India, inhabiting various geographical locations and occupying various positions in the socio-cultural hierarchy, were

Analysis of gene diversity in subdivided populations.

  • M. Nei
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1973
A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This

An Alu insertion polymorphism in a baboon hybrid zone.

A novel polymerase chain reaction (PCR) primer pair was used to analyze the frequency of insertion of the first described, nonhuman, baboon-specific Alu repetitive element in populations from the

Archaeology and Language: The Puzzle of Indo-European Origins

The curious thing about Renfrew's new book is that although it means to argue a major professional question, it is written to the educated layperson. Chapters patiently, if succinctly, expound the

A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans

It is shown that human chromosome 11 carries a recent integration of the mitochondrial control region that can be used to gain further insight into the origin of the human mitochondrial gene pool.

Alu insertion polymorphisms and human evolution: evidence for a larger population size in Africa.

The results support the African origin of modern humans in that an earlier expansion of the ancestors of African populations is indicated.