Genetic studies of autism: from the 1970s into the millennium.

@article{Rutter2000GeneticSO,
  title={Genetic studies of autism: from the 1970s into the millennium.},
  author={Michael Rutter},
  journal={Journal of abnormal child psychology},
  year={2000},
  volume={28 1},
  pages={3-14}
}
Reviewers in the 1960s and early 1970s were skeptical about any substantial role for genetic factors in the etiology of autism. A realization that the 2% rate of autism in siblings (as estimated at that time) was far above the general population base rate, and that this suggested a possible high genetic liability, led to the first small-scale twin study of autism. The replicated evidence from both twin and family studies undertaken in the 1970s and 1980s indicated both strong genetic influences… CONTINUE READING