Genetic strategies for dissecting mammalian and Drosophila voltage-dependent anion channel functions.

@article{Craigen2008GeneticSF,
  title={Genetic strategies for dissecting mammalian and Drosophila voltage-dependent anion channel functions.},
  author={William J. Craigen and Brett H Graham},
  journal={Journal of bioenergetics and biomembranes},
  year={2008},
  volume={40 3},
  pages={207-12}
}
Voltage-dependent anion channels (VDACs), also known as mitochondrial porins, are a family of small pore-forming proteins of the mitochondrial outer membrane that are found in all eukaryotes. VDACs are thought to play important roles in the regulated flux of metabolites between the cytosolic and mitochondrial compartments, in overall energy metabolism via interactions with cytosolic kinases, and a debated role in programmed cell death (apoptosis). The mammalian genome contains three VDAC loci… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…