Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism.

@article{Takos2010GeneticSI,
  title={Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism.},
  author={Adam M. Takos and Daniela Lai and Lisbeth Mikkelsen and Maher Abou Hachem and Dale Shelton and Mohammed S. Motawia and Carl Erik Olsen and Trevor L. Wang and Cathie Martin and Fred Rook},
  journal={The Plant cell},
  year={2010},
  volume={22 5},
  pages={1605-19}
}
Cyanogenesis, the release of hydrogen cyanide from damaged plant tissues, involves the enzymatic degradation of amino acid-derived cyanogenic glucosides (alpha-hydroxynitrile glucosides) by specific beta-glucosidases. Release of cyanide functions as a defense mechanism against generalist herbivores. We developed a high-throughput screening method and used it to identify cyanogenesis deficient (cyd) mutants in the model legume Lotus japonicus. Mutants in both biosynthesis and catabolism of… CONTINUE READING

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References

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Showing 1-10 of 42 references

Why are so many food plants cyanogenic?

Phytochemistry • 1998
View 2 Excerpts
Highly Influenced

Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus

M. C. Peitsch
Plant Physiol . • 1997
View 1 Excerpt
Highly Influenced

Consequences for animal production of cyanogenesis in sorghum forage and hay – A review

M. Zagrobelny, S. Bak, C. T. Ekstrøm, C. E. Olsen, B. L. Møller
Trop . Grassl . • 2007
View 1 Excerpt

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