Genetic screen for regulators of ind expression identifies shrew as encoding a novel twisted gastrulation-like protein involved in Dpp signaling.

@article{Bonds2007GeneticSF,
  title={Genetic screen for regulators of ind expression identifies shrew as encoding a novel twisted gastrulation-like protein involved in Dpp signaling.},
  author={Morgan Bonds and Jennifer L Sands and Will Poulson and Canda Harvey and Tonia Von Ohlen},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2007},
  volume={236 12},
  pages={3524-31}
}
Initiation and refinement of expression of the Ind homeodomain protein in the Drosophila embryo is coordinately regulated by global dorsoventral patterning pathways Dorsal, Egfr, and Dpp, and well as by Vnd, which positions the ventral boundary of Ind. Therefore, we set out to look for novel regulators of dorsoventral patterning by screening the Exelixis deficiency collection for modified expression of Ind. Indeed, we found deficiencies that remove components of the known signaling pathways had… CONTINUE READING