Genetic risk of acute pulmonary infections and sepsis.

  title={Genetic risk of acute pulmonary infections and sepsis.},
  author={Grant W. Waterer and Anke H. W. Bruns},
  journal={Expert review of respiratory medicine},
  volume={4 2},
The focus of this review is the genetic influence on pneumonia and sepsis. A large number of polymorphisms in a diverse collection of genes have been identified as potential candidates to explain the genetic variability in susceptibility to acute pulmonary infection and its adverse outcomes. Unfortunately, apart from polymorphisms in mannose-binding lectin, CD14 and the IgG2 receptor, there is little consensus on which polymorphisms are truly important. As well as discussing some of the major… CONTINUE READING

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