Genetic risk factors in acute coronary disease.

  title={Genetic risk factors in acute coronary disease.},
  author={Fernando Ferreira Ara{\'u}jo and Am{\'e}rico Ribeiro Santos and vitor. araujo and Isabel Henriques and Francisco Monteiro and Elsa R Meireles and Isabel Moreira and Daniel M. Lavery Grant E. Haab John C. Gyllenhaal David and Maria J{\'u}lia Maciel and Luis Manuel Cunha-Ribeiro},
  volume={29 4},
OBJECTIVE We investigate whether each of the following: HPA-1, Factor V Leiden, prothrombin gene variant and the methylene tetrahydrofolate reductase gene (MTHFR) mutation, are risk factors for acute coronary disease in Portuguese patients. MATERIAL AND METHODS 100 blood donors and 52 patients with an established diagnosis of myocardial infarction or unstable angina were evaluated for genetic risk factors, by determining HPA-1 genotype, Factor V Leiden, Prothrombin 20210 variant and MTHFR… CONTINUE READING
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