Genetic risk factors for perception of symptoms in GERD: an observational cohort study.

Abstract

BACKGROUND Genetic polymorphisms in G-protein beta-3 subunit (GNβ3) and beta-2 adrenergic receptor (ADRB2) are associated with pain and gut hypersensitivity, which can overlap with gastroesophageal reflux disease (GERD). AIM To evaluate relationships between single nucleotide polymorphisms (SNPs) within GNβ3 and ADRB2 systems, and reflux symptom burden… (More)
DOI: 10.1111/apt.14414

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