Genetic resistance to urethan-induced pulmonary adenomas in SMXA recombinant inbred mouse strains.

  title={Genetic resistance to urethan-induced pulmonary adenomas in SMXA recombinant inbred mouse strains.},
  author={Abujiang Pataer and Masahiko Nishimura and T. O. Kamoto and Kentaro Ichioka and Mitsuo Sato and Hiroshi Hiai},
  journal={Cancer research},
  volume={57 14},
Development of pulmonary adenomas (PAs) in mice is under the genetic control of multiple host genes. We have established a new set of SMXA recombinant inbred strains from PA-susceptible A/J and PA-resistant SM/J mice. The number of urethan-induced PAs was variable among substrains of the SMXA recombinant inbred strains, indicating the involvement of multiple genes. SMXA24 mice were highly resistant to PA, although they had susceptible alleles at all four known susceptibility genes, including… CONTINUE READING

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Complex interactions of new quantitative trait loci . Sluci , Sluc 2 , Sluc 3 , and Sluc 4 , that influence the susceptibility to lung cancer in the mouse

R. J. A.. De Vries Fijneman, S. S., R. C. Jansen, P. Demant
Nat . Genet . • 1996

Genetic mapping of a pulmonary adenoma resistance ( Parl ) in mouse

G. Manenti, M. Garibaldi, +7 authors T. A. Dragani

Mouse chromosome I I

D. W. Chow, M. Roller., M. M. Newhouse, A. M. Buchberg, S. A. Camper
Mamm . Genome . . • 1996

mac tivation of the PI 61 NK 4 / MTS ! gene by a chromosome translocation t ( 9 ; l 4 ) ( p 2 l†” 22 ; qI I ) in an acute lymphoblastic leukemia of B - cell type

D. Duro, 0. Bemard, +3 authors C. J. Larsen
Cancer Res . • 1996

Analysis of c - fos , c - fun , c - erbB ! , c - erbB 2 and c - myc in primary lung carcinomas and their lymph node metastases

M. VoIm, K. G. Van, J. Mattem
Clin . Exp . Metastasis • 1994

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