Genetic relatedness of the basic replicon of the virulence plasmid in shigellae and enteroinvasive Escherichia coli.

@article{Makino1988GeneticRO,
  title={Genetic relatedness of the basic replicon of the virulence plasmid in shigellae and enteroinvasive Escherichia coli.},
  author={Sou-ichi Makino and Chihiro Sasakawa and Masanosuke Yoshikawa},
  journal={Microbial pathogenesis},
  year={1988},
  volume={5 4},
  pages={267-74}
}
The regions required for replication (Rep) and for stable maintenance (Stb) of the 230 kilobase virulence plasmid, pMYSH6000, in Shigella flexneri 2a YSH6000 were identified on the restriction enzyme Sa/l fragments, C and O, respectively. The stable plasmid, pMYSH6610, consisting of adjacent fragments C and O was found to belong to the incompatibility group Fl. In all strains of shigellae and enteroinvasive Escherichia coli (EIEC) tested, virulence plasmids were found to be highly homologous… CONTINUE READING
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