Genetic regulation of linear growth

  title={Genetic regulation of linear growth},
  author={Shanna Yue and Philip E. Whalen and Youn Hee Jee},
  booktitle={Annals of pediatric endocrinology & metabolism},
Linear growth occurs at the growth plate. Therefore, genetic defects that interfere with the normal function of the growth plate can cause linear growth disorders. Many genetic causes of growth disorders have already been identified in humans. However, recent genome-wide approaches have broadened our knowledge of the mechanisms of linear growth, not only providing novel monogenic causes of growth disorders but also revealing single nucleotide polymorphisms in genes that affect height in the… CONTINUE READING
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