Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse

@article{AlMulla2006GeneticPO,
  title={Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse},
  author={Fahd Al-Mulla and Abdulla I F Behbehani and Milad S. Bitar and Govindarajulu Varadharaj and James J. Going},
  journal={Modern Pathology},
  year={2006},
  volume={19},
  pages={648-658}
}
A substantial number of patients with early-stage colorectal cancer relapse from metastatic disease. Identification of these patients by genetic profiling of their primary tumours may allow more informed follow-up and tailored administration of adjuvant therapy. Primary tumours from 70 patients with early-stage and largely microsatellite-stable colorectal cancer were profiled using metaphase-based comparative genomic hybridization (CGH) and the aberrations confirmed independently in a subset of… CONTINUE READING
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