Genetic profiling of poorly differentiated sinonasal tumours

  title={Genetic profiling of poorly differentiated sinonasal tumours},
  author={Alejandro L{\'o}pez-Hern{\'a}ndez and Blanca Vivanco and Alessandro Franchi and Elisabeth Bloemena and Virginia N Cabal and Sira Potes and Cristina Riobello and Cristina Garc{\'i}a-Incl{\'a}n and Fernando L{\'o}pez and Jos{\'e} Luis Llorente and Mario A Hermsen},
  booktitle={Scientific Reports},
The sinonasal cavities harbour a variety of rare tumour types. Many carry a poor prognosis while therapeutic options are limited. Histopathological classification can be difficult, especially for poorly differentiated tumours such as olfactory neuroblastoma (ONB), sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC). We analysed Affymetrix OncoScan genome-wide copy number profiles of these three tumour types, both as originally diagnosed and as regrouped by… CONTINUE READING
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