Genetic profiling of CLL: a ‘TP53 addict' perspective


Chronic lymphocytic leukaemia (CLL) is a B-cell malignancy with a highly variable clinical course. Whereas some patients require treatment relatively soon after diagnosis, others may stay free of symptoms for many years with a standard ‘watch and wait’ surveillance approach. Genomic analysis of asymptomatic patients and patients with progressive or relapsed… (More)
DOI: 10.1038/cddis.2015.415


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