Genetic profiling and epidermal growth factor receptor-directed therapy in nonsmall cell lung cancer.

@article{Cadranel2011GeneticPA,
  title={Genetic profiling and epidermal growth factor receptor-directed therapy in nonsmall cell lung cancer.},
  author={Jacques L Cadranel and G{\'e}rard Zalcman and Lecia V Sequist},
  journal={The European respiratory journal},
  year={2011},
  volume={37 1},
  pages={183-93}
}
The principle of preferentially selecting patients most likely to benefit from therapy according to their genetic profile has led to substantial clinical benefit in some tumour types, and has potential to considerably refine treatment in advanced nonsmall cell lung cancer (NSCLC). Effective, reliable use of molecular biomarkers to inform clinical practice requires the standardisation of testing methods and careful assessment of biomarkers' predictive and prognostic value. Although a number of… CONTINUE READING
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