Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization.

@article{IsingerEkstrand2010GeneticPO,
  title={Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization.},
  author={Anna Isinger-Ekstrand and Jan E Johansson and Mattias Ohlsson and Princy Francis and Johan Staaf and Mats J{\"o}nsson and {\AA}ke Borg and Mef Nilbert},
  journal={Cancer genetics and cytogenetics},
  year={2010},
  volume={200 2},
  pages={120-6}
}
We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative target genes were validated in an extended series. Adenocarcinomas in the distal esophagus and the… CONTINUE READING

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