Genetic predispositions to low-grade inflammation and type 2 diabetes.

@article{FernndezReal2006GeneticPT,
  title={Genetic predispositions to low-grade inflammation and type 2 diabetes.},
  author={Jos{\'e} Manuel Fern{\'a}ndez-Real},
  journal={Diabetes technology & therapeutics},
  year={2006},
  volume={8 1},
  pages={
          55-66
        }
}
Insulin resistance and cardiovascular disease share common pathophysiological mechanisms, as the chronic activation of the innate immune system. This system constitutes the first line of body's defense and is constituted by different barriers (e.g., epithelia, adipose tissue) and different blood and tissue components (e.g., macrophages, neutrophils). This system generates the acute-phase response in which different acute-phase proteins and cytokines are produced in response to different… CONTINUE READING
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