Genetic predisposition to statin myopathy.

  title={Genetic predisposition to statin myopathy.},
  author={Georgirene D. Vladutiu},
  journal={Current opinion in rheumatology},
  volume={20 6},
PURPOSE OF REVIEW Genetic predisposition to statin myopathy is a rapidly expanding area of investigation. This review summarizes the latest information on genetic risk factors associated with statin-induced myopathy. Genetic determinants involved in both pharmacokinetics of statins and metabolic muscle diseases are discussed. Data are provided on the prevalence of statin use in the United States; incidence of associated myopathy; terminology relating to statin myopathy and genetic… CONTINUE READING