Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.

@article{Babushok2016GeneticPT,
  title={Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.},
  author={Daria V. Babushok and Monica Bessler and Timothy S. Olson},
  journal={Leukemia & lymphoma},
  year={2016},
  volume={57 3},
  pages={520-36}
}
Myelodysplastic syndrome (MDS) is a clonal blood disorder characterized by ineffective hematopoiesis, cytopenias, dysplasia and an increased risk of acute myeloid leukemia (AML). With the growing availability of clinical genetic testing, there is an increasing appreciation that a number of genetic predisposition syndromes may underlie apparent de novo presentations of MDS/AML, particularly in children and young adults. Recent findings of clonal hematopoiesis in acquired aplastic anemia add… CONTINUE READING
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