Genetic predisposition to atorvastatin-induced myopathy: a case report.


WHAT IS KNOWN AND OBJECTIVE The major clinical complication of statins is a variety of muscle complaints ranging from myalgia to rhabdomyolysis. There is growing evidence that carriers of genetic polymorphisms in the enzymes and transporters implicated in statin disposition, particularly the SLCO1B1 gene, are at increased risk of myotoxicity. Our objective… (More)
DOI: 10.1111/j.1365-2710.2012.01337.x