Genetic polymorphisms of vein wall remodeling in chronic venous disease: a narrative and systematic review

@article{Bharath2014GeneticPO,
  title={Genetic polymorphisms of vein wall remodeling in chronic venous disease: a narrative and systematic review},
  author={Vighnesh Bharath and Susan R. Kahn and Alejandro Lazo-Langner},
  journal={Blood},
  year={2014},
  volume={124 8},
  pages={
          1242-50
        }
}
Chronic venous disease encompasses a spectrum of disorders caused by an abnormal venous system. They include chronic venous insufficiency, varicose veins, lipodermatosclerosis, postthrombotic syndrome, and venous ulceration. Some evidence suggests a genetic predisposition to chronic venous disease from gene polymorphisms associated mainly with vein wall remodeling. The literature exploring these polymorphisms has not been reviewed and compiled thus far. In this narrative and systematic review… CONTINUE READING

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