Genetic polymorphisms of glutathione S-transferase M1, T1, and P1, and the assessment of oxidative damage in infertile men with varicoceles from northwestern China.

@article{Tang2012GeneticPO,
  title={Genetic polymorphisms of glutathione S-transferase M1, T1, and P1, and the assessment of oxidative damage in infertile men with varicoceles from northwestern China.},
  author={Kaifa Tang and Wei Xue and Yao Wen Xing and Shaoyuan Xu and Qifei Wu and Ruizhe Liu and Xinyang Wang and Junping Xing},
  journal={Journal of andrology},
  year={2012},
  volume={33 2},
  pages={257-63}
}
Our objective was to investigate the genetic polymorphisms of the glutathione S-transferase M1, T1, and P1 genes (GSTM1, GSTT1, and GSTP1) and to assess the oxidative damage in infertile men with varicoceles from northwestern China. A total of 65 infertile men with varicoceles and 30 controls were included in the study. Multiplex polymerase chain reaction and polymerase chain reaction-restriction fragment length polymorphism analyses were used to identify the genotypes. Sperm DNA damage was… CONTINUE READING

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