Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus

@inproceedings{Lin2009GeneticPO,
  title={Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus},
  author={Julie Lin and Frank B Hu and Lu Qi and Gary C. Curhan},
  booktitle={BMC nephrology},
  year={2009}
}
BACKGROUND Increased activation of the renin-angiotensin system (RAS) may be important in promoting coronary heart disease (CHD) and renal dysfunction, but limited data are available on associations between angiotensin type 1 receptor (AGT1R) and angiotensinogen (AGT) genotypes in type 2 diabetes. METHODS Study participants were diabetics from the Health Professionals Follow-Up Study (HPFS) and the Nurses' Health Study (NHS). We analyzed single nucleotide polymorphisms (SNPs) associated with… CONTINUE READING

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References

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Showing 1-10 of 37 references

Genetic variation of the renin-angiotensin sys- tem and chronic kidney disease progression in black individ- uals in the atherosclerosis risk in communities study

  • CC Hsu
  • J Am Soc Nephrol
  • 2006
Highly Influential
6 Excerpts

Gender differences in the renal response to renin-angiotensin system blockade

  • JA Miller
  • J Am Soc Nephrol
  • 2006
1 Excerpt

Influence of gender and genetic variability on plasma angiotensin peptides

  • A Reyes-Engel
  • J Renin Angiotensin Aldosterone Syst
  • 2006
1 Excerpt

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