Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma.

@article{Ren2004GeneticPI,
  title={Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma.},
  author={Zefang Ren and Qiuyin Cai and Xiao-ou Shu and Hui Cai and Jia-rong Cheng and Wong Kai Wen and Yu-tang Gao and Wei Zheng},
  journal={Cancer},
  year={2004},
  volume={101 2},
  pages={251-7}
}
BACKGROUND In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the Shanghai Breast Cancer Study. METHODS Included in the current investigation were 1193 women with breast carcinoma (case patients) and 1310 healthy women from the same community… CONTINUE READING

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Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study.

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Pituitary growth hormone and growth hormone-releasing hormone receptor genes and associations with mammographic measures and serum growth hormone.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2005
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