Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival

@article{Shen2012GeneticPI,
  title={Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival},
  author={Jing Shen and Marilie Denise Gammon and Mary Beth Terry and Patrick Terrence Bradshaw and Qiao Wang and Susan L. Teitelbaum and Alfred I. Neugut and Regina M. Santella},
  journal={Breast Cancer Research and Treatment},
  year={2012},
  volume={134},
  pages={393-400}
}
The impact of genetic variants in telomere pathway genes on telomere length and breast cancer survival remains unclear. We hypothesized that telomere length and genetic variants of telomere pathway genes are associated with survival among breast cancer patients. A population-based cohort study of 1,026 women diagnosed with a first primary breast cancer was conducted to examine telomere length and 52 genetic variants of 9 telomere pathway genes. Adjusted Cox regression analysis was employed to… CONTINUE READING
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