Genetic polymorphisms in DNA repair genes XPC, XPD, and XRCC4, and susceptibility to Helicobacter pylori infection-related gastric antrum adenocarcinoma in Guangxi population, China.

@article{Long2010GeneticPI,
  title={Genetic polymorphisms in DNA repair genes XPC, XPD, and XRCC4, and susceptibility to Helicobacter pylori infection-related gastric antrum adenocarcinoma in Guangxi population, China.},
  author={Xi-Dai Long and Yun Ma and Yong-zhi Huang and Yun Jae Yi and Qiu-Xiang Liang and Ai-Min Ma and Li-ping Zeng and G Fu},
  journal={Molecular carcinogenesis},
  year={2010},
  volume={49 6},
  pages={611-8}
}
Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of gastric antrum adenocarcinoma (GAA) related to Helicobacter pylori infection. This study, including 361 GAAs and 616 controls without any evidence of tumors, was designed to evaluate the association between the polymorphisms of DNA repair genes XPC Ala499Val (RS#2228000) and Lys939Gln (RS#2228001), XPD Lys751Gln (RS#13181), and XRCC4 Ala247Ser (RS#3734091… CONTINUE READING

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