Genetic polymorphisms for the study of multifactorial stroke.

@article{Bersano2008GeneticPF,
  title={Genetic polymorphisms for the study of multifactorial stroke.},
  author={Anna Bersano and Elena Ballabio and N Bresolin and Livia Candelise},
  journal={Human mutation},
  year={2008},
  volume={29 6},
  pages={
          776-95
        }
}
Single-gene disorders explain only a minority of stroke cases. Stroke represents a complex trait, which is usually assumed to be polygenic. On this topic, the role of a wide number of candidate genes has been investigated in stroke through association studies, with controversial results. Therefore, it is difficult for the clinician to establish the validity and the level of clinical applicability of the previously reported associations between genetic factors and stroke. This review is an… CONTINUE READING
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