Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort

@inproceedings{Kedenko2014GeneticPA,
  title={Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort},
  author={Lyudmyla Kedenko and Claudia Lamina and Igor Kedenko and Barbara Kollerits and Tobias Kiesslich and Bernhard Iglseder and Florian Kronenberg and Bernhard Paulweber},
  booktitle={BMC Medical Genetics},
  year={2014}
}
SIRT1 and FOXO1 interact with each other in multiple pathways regulating aging, metabolism and resistance to oxidative stress and control different pathways involved in atherosclerotic process. It is not known, if genetic polymorphisms (SNPs) at the SIRT1 and FOXO1 have an influence on carotid atherosclerosis. Intima-media thickness (IMT) was measured on… CONTINUE READING