Genetic polymorphisms and human sensitivity to opioid analgesics.

Abstract

Opioid analgesics are commonly used for the treatment of acute as well as chronic, moderate to severe pain. Well-known, however, is the wide interindividual variability in sensitivity to opioids that exists, which has often been a critical problem in pain treatment. To date, only a limited number of studies have addressed the relationship between human… (More)
DOI: 10.1007/978-1-60327-323-7_29

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