Genetic polymorphism on endothelial nitric oxide synthase affects endothelial activation and inflammatory response during the acute phase of myocardial infarction.

@article{Antoniades2005GeneticPO,
  title={Genetic polymorphism on endothelial nitric oxide synthase affects endothelial activation and inflammatory response during the acute phase of myocardial infarction.},
  author={Charalambos Antoniades and Dimitris Tousoulis and Carmen Vasiliadou and Christos Pitsavos and Christina Chrysochoou and Demosthenes B. Panagiotakos and Costas Tentolouris and Kyriakoula Marinou and Nikolaos Koumallos and Christodoulos Stefanadis},
  journal={Journal of the American College of Cardiology},
  year={2005},
  volume={46 6},
  pages={1101-9}
}
OBJECTIVES This study sought to evaluate the effect of genetic polymorphism G894T on endothelial nitric oxide synthase (eNOS); on the risk for myocardial infarction (MI); and on the release of von Willebrand factor (vWF), interleukin (IL)-6, IL-1b, and oxidized low-density lipoprotein (ox-LDL) levels during the acute phase of MI and one year after the event. BACKGROUND Genetic polymorphism G894T on eNOS has been associated with increased cardiovascular risk. However, its role during the acute… CONTINUE READING
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