Genetic polymorphism of the A subunit of human coagulation factor XIII.

@article{Board1979GeneticPO,
  title={Genetic polymorphism of the A subunit of human coagulation factor XIII.},
  author={Philip G Board},
  journal={American journal of human genetics},
  year={1979},
  volume={31 2},
  pages={116-24}
}
Utilizing a fluorescent technique for the localization of transglutaminase activity after electrophoresis on thin layer agarose gels, we observed a new polymorphism of coagulation factor XIII in both platelets and plasma. The electrophoretic pattern was that of a dimeric protein. Homozygotes gave a single band, while heterozygotes presented a three banded pattern. The polymorphism was found to be due to variation of the A subunit. Data from Australian blood donors indicate that the A subunit of… CONTINUE READING

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