Genetic polymorphism of interferon-gamma, interferon-gamma receptor, and interferon regulatory factor-1 genes in patients with hepatitis B virus infection.

@article{Cheong2006GeneticPO,
  title={Genetic polymorphism of interferon-gamma, interferon-gamma receptor, and interferon regulatory factor-1 genes in patients with hepatitis B virus infection.},
  author={Jae Youn Cheong and Sung Won Cho and Soon Gee Chung and Jung Ae Lee and Marie Yeo and Hee Jung Wang and Jong Eun Lee and Ki Baik Hahm and Jin Hong Kim},
  journal={Biochemical genetics},
  year={2006},
  volume={44 5-6},
  pages={246-55}
}
The natural history of hepatitis B virus (HBV) infection is probably related to host immune factors. Interferon-gamma (IFN-gamma) plays significant roles in immune defense. This study was undertaken to investigate the association between HBV infection and single nucleotide polymorphisms (SNPs) of IFN-gamma, IFN-gamma receptor (IFNGR)-1 and 2, and interferon regulatory factor (IRF)-1 genes. Between March 2002 and December 2002, 614 Korean patients were enrolled in two different groups: an HBV… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…