Genetic polymorphism of VEGF-1154 (A/G) in laryngeal squamous cell carcinoma.

  title={Genetic polymorphism of VEGF-1154 (A/G) in laryngeal squamous cell carcinoma.},
  author={Zeynep Nil Unal and M Fatih Unal and Ozlen Tubay Bağdatoğlu and G{\"u}rb{\"u}z Polat and Uğur Atik},
  journal={Archives of medical research},
  volume={39 2},
BACKGROUND Angiogenesis has been shown to be increased in various human tumors including head and neck squamous cell carcinoma (SCC). Vascular endothelial growth factor (VEGF) is thought to be one of the most important angiogenic factors in tumorigenesis. In this study, we aimed to investigate whether polymorphism of VEGF-1154 (A/G) genotypes are associated with the risk of laryngeal SCC. METHODS A prospective, randomized, case-control study in a tertiary university hospital was done. The… CONTINUE READING