Genetic polymorphism and linkage disequilibrium of the HLA-DP region in Basques from Navarre (Spain).

@article{PrezMiranda2004GeneticPA,
  title={Genetic polymorphism and linkage disequilibrium of the HLA-DP region in Basques from Navarre (Spain).},
  author={Ana M P{\'e}rez-Miranda and Miguel A. Alfonso-S{\'a}nchez and Maria Concepcion Vidales and Rosario Calder{\'o}n and Jos{\'e} Antonio de la Pe{\~n}a},
  journal={Tissue antigens},
  year={2004},
  volume={64 3},
  pages={264-75}
}
In this work, a sample of 116 individuals from an autochthonous Basque population (northern Navarre, Spain) was typed at the DNA level for HLA-DPA1 and HLA-DPB1 loci, with the aim of analysing the genetic polymorphism and the linkage disequilibrium (LD) of the HLA-DP region. In this Basque subpopulation, the most frequent alleles were *0103 (0.767) and *0201 (0.185) for DPA1 locus, whereas for DPB1 locus the *0401 allele was predominant (0.307). Accordingly, the most frequent haplotype was DPA1… CONTINUE READING
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