Genetic polymorphism

  title={Genetic polymorphism},
  author={Edmund Brisco Ford},
  journal={Proceedings of the Royal Society of London. Series B. Biological Sciences},
  pages={350 - 361}
  • E. Ford
  • Published 2 February 2020
  • Biology
  • Proceedings of the Royal Society of London. Series B. Biological Sciences
The title of this Symposium ‘From Mendel’s factors to the genetic code’ emphasizes a single aspect of genetic research. That is unfortunate in a subject of such wide scope. Even in the most general terms, it naturally involves far more than analysing the fine structure of the genetic material and the physiological paths by which the genes produce the characters for which they are responsible. For it is of course essential to study the functions of those characters: the ways in which they… 
Genetical changes in mice and men.
The easiest situation to investigate, from the genetical point ofview, is a population which is variable with respect to some trait, when it is possible to compare two organisms from the same place to see if either of them is better fitted to survive than the other in a given set of circumstances, whether the observed variation is adaptive.
A Theoretical Scheme of the Large-Scale Evolution by Generating New Genes from Gene Duplication
Doubts remain about whether the gradual accumulation of such mutants gives rise to radically new organs such as wings and eyes in Darwinian evolution.
Admixture can readily lead to the formation of supergenes
It is shown that the evolution of inversions in differentiated populations connected by gene flow leads to an increase in frequency of poorly adapted, immigrant haplotypes, and bring new light into the importance of admixture in the formation of new genetic architectures.
Environmental Heterogeneity: A Problem of Contradictory Selection Pressures, Gene Flow, and Local Polymorphism
The interaction of gene flow with contradictory selective pressures that are caused by environmental heterogeneity has been investigated by computer simulation and conclusions are drawn concerning the evolutionary significance of gene Flow.
Genetic influences on carbohydrate digestion
The present review focuses on genetic variations that are of relevance to digestion of the sugars and starches that form a major part of human diets, and considers these in relation to the evolution of the authors' species.
Polymorphism of the Mouse H‐2 Loci
In principle, four situations may occur when a gene/4 mutates to a: the individual carryinga fails to reproduce and the mutation disappears from the population with the death of its bearer, the bearer of the mutation does reproduce and does transmit the mutation to its progeny; the mutant allele stays in the population at a low frequency for a while but then, by chance or because it is selected against, disappears again.
A comprehensive test for negative frequency-dependent selection
A general review of NFDS is presented and some problems with previous works are pointed out to develop reasonable alternative research strategies for testing NFDS and results provide unequivocal empirical support for NFDS in a natural system.
The Evolution and Ecology of Permanent Translocation Heterozygotes
Permanent translocation heterozygotes are known from at least 57 species of flowering plants. They often share certain features of chromosome morphology, though none are universal or required. Many
Cloning quantitative trait loci by insertional mutagenesis
It would appear that successful implementation of experiments of this sort will require the introduction of multiple independent inserts in the original parent individuals, by means of repeated transformation, or use of transposable elements as inserts.