Genetic mutations in Turkish population with pulmonary embolism and deep venous thrombosis.

@article{Kupeli2011GeneticMI,
  title={Genetic mutations in Turkish population with pulmonary embolism and deep venous thrombosis.},
  author={Elif Kupeli and Hasibe Verdi and Abdullah Şimşek and Fatma Belgin Ataç and Fusun Oner Eyuboglu},
  journal={Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis},
  year={2011},
  volume={17 6},
  pages={E87-94}
}
Venous thromboembolism (VTE) is a universal health hazard. Inherited and acquired risk factors increase the risk of VTE. We evaluated the relationship between factor V (G1691A, A1090G, and A1299G), prothrombin (PT G20210A), methylenetetrahydrofolate reductase (MTHFR C677T) mutations, plasminogen activator inhibitor 1 (PAI-1 -675) polymorphism, and VTE in Turkish population. In all, 80 patients with VTE and 104 controls were included. Heterozygous factor V Leiden (FVL) mutation was significantly… CONTINUE READING