Genetic modulation of nephrocalcinosis in mouse models of ectopic mineralization: The Abcc6tm1Jfk and Enpp1asj mutant mice


Ectopic mineralization of renal tissues in nephrocalcinosis is a complex, multifactorial process. The purpose of this study was to examine the role of genetic modulation and the role of diet in nephrocalcinosis using two established mouse models of ectopic mineralization, Abcc6tm1Jfk and Enpp1asj mice, which serve as models for pseudoxanthoma elasticum and… (More)
DOI: 10.1038/labinvest.2014.52


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