Genetic metabolic polymorphisms and the risk of cancer: a review of the literature.

@article{Derrico1996GeneticMP,
  title={Genetic metabolic polymorphisms and the risk of cancer: a review of the literature.},
  author={A D'errico and Emanuela Taioli and X Chen and Paolo Vineis},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={1996},
  volume={1 3},
  pages={149-73}
}
Abstract The purpose of this paper is to systematically analyse the design and results of epidemiological studies on the association between various types of cancer (lung, bladder, breast, colon, stomach) and four genetically-based metabolic polymorphisms, involved in the metabolism of several carcinogens (glutathione-S-transferase M1, debrisoquine hydroxylase, N acetyltransferase, aryl hydrocarbon hydroxylase). These inherited polymorphisms usually cause modifications in the quality or… CONTINUE READING

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